Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates

@inproceedings{Terrin2014EfficacyOP,
  title={Efficacy of paracetamol for the treatment of patent ductus arteriosus in preterm neonates},
  author={Gianluca Terrin and Francesca Conte and Antonella Scipione and Erica Bacchio and Maria Giulia Conti and Rosalia Ferro and Flavia Ventriglia and Mario De Curtis},
  booktitle={Italian journal of pediatrics},
  year={2014}
}
Inhibitors of the cyclo-oxygenase component of prostaglandin-H2 synthetase, namely indomethacin and ibuprofen, are commonly used in the treatment of hemodynamically significant patent ductus arteriosus. These drugs are associated with serious adverse events, including gastrointestinal perforation, renal failure and bleeding. The role of paracetamol, an inhibitor of the peroxidase component of prostaglandin-H2 synthetase, has been proposed for the treatment of patent ductus arteriosus. We report… CONTINUE READING
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Intravenous paracetamol for patent ductus arteriosus in premature infants - a lower dose

  • KS Tekgunduz, N Ceviz, +4 authors C Yolcu
  • Neonatology
  • 2013
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