Efficacy of oral moxifloxacin for aerobic vaginitis

@article{Wang2015EfficacyOO,
  title={Efficacy of oral moxifloxacin for aerobic vaginitis},
  author={Chaomeng Wang and C Han and Nv Geng and Aiping Fan and Yuliang Wang and Y Yue and H Y Zhang and Fengxia Xue},
  journal={European Journal of Clinical Microbiology \& Infectious Diseases},
  year={2015},
  volume={35},
  pages={95-101}
}
  • C. Wang, C. Han, +5 authors F. Xue
  • Published 2015
  • Medicine
  • European Journal of Clinical Microbiology & Infectious Diseases
The purpose of this study was to investigate the therapeutic efficacy of oral moxifloxacin for aerobic vaginitis (AV). We also identified factors that are associated with therapeutic efficacy. This prospective study enrolled general gynecological outpatients at Tianjin Medical University General Hospital between September 2012 and May 2014. Women diagnosed with AV (n = 102) were recruited. All enrolled women were treated with oral moxifloxacin, 400 mg once daily for 6 days (one course… Expand
Aerobic vaginitis in late pregnancy and outcomes of pregnancy
  • C. Han, Huiyang Li, +6 authors F. Xue
  • Medicine
  • European Journal of Clinical Microbiology & Infectious Diseases
  • 2018
TLDR
A higher incidence of premature rupture of membranes (PROM) was significantly associated with AV, and Clinicians should pay more attention to vaginal microbiota evaluations during pregnancy. Expand
How to diagnose and treat aerobic and desquamative inflammatory vaginitis
TLDR
A practical approach to investigating and managing abnormal vaginal discharge in a specialist setting where near-patient microscopy is available is focused on. Expand
Vaginal bacterial profiles of aerobic vaginitis: a case-control study.
TLDR
Multiple aerobes and facultative anaerobes were involved in vaginal dysbiosis, which was associated with decreasing L. crispatus levels, and Probiotics containing L. crisatus may be potential supplementary agents. Expand
Abnormal vaginal flora in symptomatic non-pregnant and pregnant women in a Greek hospital: a prospective study
TLDR
Clinicians should include AV in the differential diagnosis of vaginitis, while microbiologists should take into account the growth of aerobic bacteria in vaginal cultures originating from women with microscopic findings of AV. Expand
The Effectiveness of Single-Dose Azithromycin Versus its Combination With Moxifloxacin Based on the Treatment of Chlamydial Cervicitis: A Study Protocol for a Randomized Clinical Trial
TLDR
This trial will be the first study to explore the effects of single-dose azithromycin in combination with moxifloxacin in the treatment of chlamydial cervicitis and the results of this trial will further reveal the diagnostic value of syndromic and etiologic methods in the diagnosis of chladydia trachomatis. Expand
Aerobic vaginitis: no longer a stranger.
TLDR
AV is characterized by abnormal (dysbiotic) vaginal microflora containing aerobic, enteric bacteria, variable levels of vaginal inflammation and deficient epithelial maturation, and can co-occur with other entities, such as BV and candidiasis. Expand
Bacterial Vaginitis and Vaginosis
TLDR
The topic of this chapter is highly intertwined with the indigenous microbiota of the lower female genital tract, and this chapter will not consider the fungal causes of vaginal symptoms (Candida) or protozoon (Trichomonas) organisms causing vaginitis or non-microbial conditions. Expand

References

SHOWING 1-10 OF 26 REFERENCES
Topical Kanamycin: an Effective Therapeutic Option in Aerobic Vaginitis
TLDR
The data suggest that the topical use of kanamycin could be considered a specific antibiotic for the therapy of this new pathology of aerobic vaginitis. Expand
Aerobic vaginitis and mixed infections: comparison of clinical and laboratory findings
TLDR
AV is a common vaginal infection, and it is often mixed with other infections, especially VVC, BV and TV, and an appropriate course should be selected taking the severity of AV into consideration. Expand
Management of Aerobic Vaginitis
TLDR
The therapeutic choice for ‘aerobic vaginitis’ should take into consideration an antibiotic characterized by an intrinsic activity against the majority of bacteria of fecal origin, bactericidal effect and poor/absent interference with the vaginal microbiota. Expand
Microbiological/clinical characteristics and validation of topical therapy with kanamycin in aerobic vaginitis: a pilot study.
TLDR
The results showed the validity of the treatment with kanamycin intravaginally in this recently recognised disease, with a direct correlation with recovery of vaginal homeostasis demonstrated by the normalisation of the vaginal pH and by the presence of lactobacilli, only in Kanamycin treated group. Expand
Prevalence and treatment of aerobic vaginitis among non-pregnant women: evaluation of the evidence for an underestimated clinical entity
TLDR
Evaluating the evidence on the prevalence of aerobic vaginitis among symptomatic non-pregnant women, as well as the treatment and outcomes of women with diagnosed AV, suggests that the prevalence is not negligible, while the likelihood of possible AV is considerable. Expand
Moxifloxacin in the treatment of skin and skin structure infections
  • D. Guay
  • Medicine
  • Therapeutics and clinical risk management
  • 2006
TLDR
Moxifloxacin penetrates well into inflammatory blister fluid and muscle and subcutaneous adipose tissues and should thus be a reasonable option for the treatment of skin and skin structure infections (SSSIs). Expand
Chlamydial infection in a high risk population: association with vaginal flora patterns
TLDR
A high rate of chlamydial infection was found in this population of high risk Brazilian women and chlamydia infection is associated with aerobic vaginitis. Expand
In vitro antibacterial activity of moxifloxacin against hospital isolates: a multicentre study.
  • C. Soussy, J. Nguyen, +9 authors P. Courvalin
  • Biology, Medicine
  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2003
TLDR
The comparatively high in vitro activity of moxifloxacin against Gram-positive cocci and other pathogens isolated from community-acquired respiratory tract infections is confirmed. Expand
Microbiological Analysis of a Prospective, Randomized, Double-Blind Trial Comparing Moxifloxacin and Clindamycin in the Treatment of Odontogenic Infiltrates and Abscesses
TLDR
The analysis suggests that viridans group streptococci and Neisseria spp. Expand
Desquamative inflammatory vaginitis: a new subgroup of purulent vaginitis responsive to topical 2% clindamycin therapy.
  • J. Sobel
  • Medicine
  • American journal of obstetrics and gynecology
  • 1994
TLDR
Evidence suggests a microbial, possibly gram-positive coccal, cause for this syndrome, although a specific bacterial species responsible for all cases has not been identified, represents an uncommon cause of purulent vaginitis with unique clinical and laboratory characteristics. Expand
...
1
2
3
...