Efficacy of oral irinotecan against neuroblastoma xenografts.


The efficacy of the topoisomerase I inhibitor, 7-ethyl-10-(4-[1-piperidino]-1-piperidino)-carbonyloxy-camptotheci n (irinotecan, CPT-11), administered by oral gavage has been examined against a panel of six independently derived neuroblastoma xenografts. Irinotecan was administered either daily for 5 days on 12 consecutive weeks ¿(d x 5)12¿ or for 5 days on… (More)


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@article{Thompson1997EfficacyOO, title={Efficacy of oral irinotecan against neuroblastoma xenografts.}, author={J. Thompson and William C. Zamboni and P. Cheshire and Lauren Richmond and X. Luo and Janet A. Houghton and Connie Stewart and Paula Houghton}, journal={Anti-cancer drugs}, year={1997}, volume={8 4}, pages={313-22} }