Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.

@article{Tohen2003EfficacyOO,
  title={Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression.},
  author={Mauricio Tohen and Eduard Vieta and Joseph R. Calabrese and Terence A. Ketter and Gary Sachs and Charles Bowden and Philip B. Mitchell and Franca Centorrino and Richard C Risser and Robert W. Baker and Angela R Evans and Karin Beymer and Sanjay Dub{\'e} and Gary D. Tollefson and Alan Breier},
  journal={Archives of general psychiatry},
  year={2003},
  volume={60 11},
  pages={1079-88}
}
BACKGROUND Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. OBJECTIVE To examine the use of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. DESIGN Double-blind, 8-week, randomized controlled trial. SETTING Eighty-four sites (inpatient… CONTINUE READING
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Bipolar (REPRINTED) ARCH GEN PSYCHIATRY

SA Hlastala, E Frank, +3 authors DJ. Kupfer
NOV • 2003

Practice guideline for the treatment of patients with bipolar disorder ( revision )

GL Zornberg, HG Pope
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