Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats.

@article{Kalailingam2014EfficacyON,
  title={Efficacy of natural diosgenin on cardiovascular risk, insulin secretion, and beta cells in streptozotocin (STZ)-induced diabetic rats.},
  author={Pazhanichamy Kalailingam and Bhuvaneswari Kannaian and Eevera Tamilmani and Rajendran Kaliaperumal},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2014},
  volume={21 10},
  pages={1154-61}
}
Costus igneus, has been prescribed for the treatment of diabetic mellitus in India for several years. The aim of this study is to investigate the effects of plant derived diosgenin on cardiovascular risk, insulin secretion, and pancreatic composition through electron microscopical studies of normal and diabetic rats. Diosgenin at a dose of 5 or 10mg/kg per body weight (bw) was orally administered as a single dose per day to diabetic induced rats for a period of 30 days. The effect of diosgenin… CONTINUE READING
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