Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials.

@article{Huser2009EfficacyOM,
  title={Efficacy of multicomponent treatment in fibromyalgia syndrome: a meta-analysis of randomized controlled clinical trials.},
  author={Winfried H{\"a}user and Kathrin Bernardy and B Arnold and Martin Offenb{\"a}cher and Marcus Schiltenwolf},
  journal={Arthritis and rheumatism},
  year={2009},
  volume={61 2},
  pages={
          216-24
        }
}
OBJECTIVE To systematically review the efficacy of multicomponent treatment of fibromyalgia syndrome (FMS). METHODS We screened Medline, PsychINFO, Scopus, and the Cochrane Library (through December 2007), as well as reference sections of original studies, reviews, and evidence-based guidelines. Randomized controlled trials (RCTs) on the multicomponent treatment (at least 1 educational or other psychological therapy with at least 1 exercise therapy) of FMS were analyzed. RESULTS We included… 
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322 Citations

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Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials

An aerobic exercise programme for FMS patients should consist of land-based or water-based exercises with slight to moderate intensity two or three times per week for at least 4 weeks, and continuing exercise was associated with positive outcomes at follow-up.

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This systematic review will synthesize evidence on the effectiveness of multicomponent treatment in patients with fibromyalgia and could add important evidence in the treatment of FM to improve clinical practice and decision-making/actions in this field.

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A quantitative analysis of the efficacy and harms of antidepressants in the management of adult FMS patients, using Cohen’s categories, found the effect size on pain was small and the ones on sleep, fatigue, depression and HRQOL were not substantial.

articleEfficacy of different types of aerobic exercise in fibromyalgia syndrome : a systematic review and meta-analysis of randomised controlled trials

An aerobic exercise programme for FMS patients should consist of land-based or water-based exercises with slight to moderate intensity two or three times per week for at least 4 weeks, and positive effects on depressed mood, HRQOL and physical fitness could be maintained at follow-up.

A systematic review of the effects of strength training in patients with fibromyalgia: clinical outcomes and design considerations

Current evidence demonstrates that ST is beneficial and can be used to treat FM, with increased functional capacity and quality of life.

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It was found that a higher level of depression was a predictor of poor outcome in FM (moderate evidence) and the baseline status, specific patient profiles, belief in fate, disability, and pain were predictors of the outcome of multidisciplinary treatment.

Comparative efficacy of pharmacological and non-pharmacological interventions in fibromyalgia syndrome: network meta-analysis

Benefits of pharmacological treatments in FMS are of questionable clinical relevance and evidence for benefits of non-pharmacological interventions is limited, but a combination of pregabalin or SNRIs as pharmacological interventions and multicomponent therapy, aerobic exercise and CBT as non- PHARMaceutical interventions seems most promising for the management of FMS.

Proportion of contextual effects in the treatment of fibromyalgia—a meta-analysis of randomised controlled trials

More than half of the treatment effect in fibromyalgia RCTs results from non-specific contextual factors, which suggests that optimising contextual care may enhance treatment effects and improve outcomes.
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