Efficacy of miltefosine for Bolivian cutaneous leishmaniasis.

  title={Efficacy of miltefosine for Bolivian cutaneous leishmaniasis.},
  author={J. M. Fernandez Soto and Jaime Rea and Margarita Balderrama and Julia T Toledo and Paula Soto and Luis Valda and Jonathan Berman},
  journal={The American journal of tropical medicine and hygiene},
  volume={78 2},
Oral miltefosine (2.5 mg/kg/d for 28 days) was compared with intramuscular antimony (20 mg/kg/d for 20 days) in the treatment of cutaneous leishmaniasis caused by Leishmania braziliensis in Palos Blancos, Bolivia. The cure rates with 6 months of follow-up were statistically similar: 36 of 41 evaluable miltefosine patients (88%) versus 15 of 16 (94%) evaluable antimony patients. However, antimony cured more rapidly, because, by 1 month after therapy, 31 of 44 miltefosine patients (70%) compared… CONTINUE READING


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