Efficacy of maropitant for treatment and prevention of emesis caused by intravenous infusion of cisplatin in dogs.

Abstract

OBJECTIVE To evaluate the efficacy of maropitant, a novel neurokinin-1 receptor antagonist, to treat and prevent emesis caused by IV infusion of a chemotherapeutic dose of cisplatin (70 mg/m(2)) in dogs. ANIMALS 64 healthy 6-month-old Beagles (32 males and 32 females). PROCEDURES To evaluate the effect of maropitant on ongoing emesis, 24 dogs were… (More)

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