Efficacy of hypertonic saline dextran fluid resuscitation for patients with hypotension from penetrating trauma.

@article{Wade2003EfficacyOH,
  title={Efficacy of hypertonic saline dextran fluid resuscitation for patients with hypotension from penetrating trauma.},
  author={Charles E. Wade and James J. Grady and George C. Kramer},
  journal={The Journal of trauma},
  year={2003},
  volume={54 5 Suppl},
  pages={S144-8}
}
BACKGROUND The purpose of this study was to assess whether the administration of hypertonic saline dextran (HSD) was detrimental when administered to patients who were hypotensive because of penetrating injuries to the torso. The administration of HSD causes an immediate and sustained increase in blood pressure that could contribute to an increase in bleeding in the presence of uncontrolled hemorrhage. We prospectively designed a series of questions to be addressed by a meta-analysis of… CONTINUE READING