Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study.

@article{Vesikari2007EfficacyOH,
  title={Efficacy of human rotavirus vaccine against rotavirus gastroenteritis during the first 2 years of life in European infants: randomised, double-blind controlled study.},
  author={Timo Vesikari and Aino V Karvonen and Roman Prymula and Volker Schuster and Juan Carlos Tejedor and Robert Cohen and François Meurice and Htay Htay Han and Silvia Damaso and Alain Bouckenooghe},
  journal={Lancet},
  year={2007},
  volume={370 9601},
  pages={1757-63}
}
BACKGROUND We aimed to assess the efficacy of the oral live attenuated human rotavirus vaccine Rotarix (RIX4414) for prevention of rotavirus gastroenteritis in European infants during their first 2 years of life. METHODS 3994 study participants were enrolled from six countries and were randomly assigned two oral doses of either RIX4414 (n=2646) or placebo (n=1348), which were coadministered with the first two doses of specific childhood vaccinations. Follow-up for gastroenteritis episodes was… CONTINUE READING
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