Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks.

@article{Craig2009EfficacyOH,
  title={Efficacy of human C1 esterase inhibitor concentrate compared with placebo in acute hereditary angioedema attacks.},
  author={Timothy John Craig and Robyn J. Levy and Richard L. Wasserman and Againdra K. Bewtra and David S. Hurewitz and Krystyna Obtułowicz and Avner Reshef and Bruce Ritchie and Dumitru Moldovan and Todor Shirov and Vesna Grivcheva-Panovska and Peter C. Kiessling and H. -O. Keinecke and J A Bernstein},
  journal={The Journal of allergy and clinical immunology},
  year={2009},
  volume={124 4},
  pages={801-8}
}
BACKGROUND Hereditary angioedema caused by C1 esterase inhibitor deficiency is a rare disorder. OBJECTIVE To compare the efficacy of pasteurized C1 esterase inhibitor concentrate (Berinert, CSL Behring) at intravenous doses of 10 or 20 U/kg body weight with placebo in the treatment of single, acute abdominal or facial attacks in patients with hereditary angioedema. METHODS This was a randomized, double-blind, placebo-controlled study in 125 patients with type I or II hereditary angioedema… CONTINUE READING
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Safety and efficacy of pasteurized C1 inhibitor concentrate (Berinert P) in hereditary angioedema: a review

  • J de Serres, A Gr€oner, J. Lindner
  • Transfus Apher Sci 2003;29:247-54
  • 2003
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