Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.

@article{Huo2015EfficacyOF,
  title={Efficacy of folic acid therapy in primary prevention of stroke among adults with hypertension in China: the CSPPT randomized clinical trial.},
  author={Yong Huo and Jianping Li and Xianhui Qin and Yining Huang and Xiaobin Wang and Rebecca F. Gottesman and Genfu Tang and Binyan Wang and Dafang Chen and Mingli He and Jia Fu and Yefeng Cai and Xiuli Shi and Yan Zhang and Yi-min Cui and Ningling Sun and Xiao-ying Li and Xiaoshu Cheng and Jian'an Wang and Xinchun Yang and Tianlun Yang and Chuanshi Xiao and Gang Zhao and Qiang Dong and Dingliang Zhu and Xian Wang and Junbo Ge and Lianyou Zhao and Dayi Hu and Lisheng Liu and Fan fan Hou},
  journal={JAMA},
  year={2015},
  volume={313 13},
  pages={
          1325-35
        }
}
  • Yong Huo, Jianping Li, +28 authors Fan fan Hou
  • Published in JAMA 2015
  • Medicine
  • IMPORTANCE Uncertainty remains about the efficacy of folic acid therapy for the primary prevention of stroke because of limited and inconsistent data. OBJECTIVE To test the primary hypothesis that therapy with enalapril and folic acid is more effective in reducing first stroke than enalapril alone among Chinese adults with hypertension. DESIGN, SETTING, AND PARTICIPANTS The China Stroke Primary Prevention Trial, a randomized, double-blind clinical trial conducted from May 19, 2008, to… CONTINUE READING

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    SU.FOL.OM3 Collaborative Research Original Investigation Folic Acid for Stroke Prevention in Hypertension

    • P Galan, E Kesse-Guyot, +3 authors S Hercberg
    • JAMA April
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