Efficacy of ezetimibe/simvastatin 10/20 and 10/40 mg compared with atorvastatin 20 mg in patients with type 2 diabetes mellitus.

@article{Constance2007EfficacyOE,
  title={Efficacy of ezetimibe/simvastatin 10/20 and 10/40 mg compared with atorvastatin 20 mg in patients with type 2 diabetes mellitus.},
  author={Christian M Constance and Sabine Westphal and Namsik Chung and Margaret E Lund and Christine McCrary Sisk and Amy O. Johnson-Levonas and Rachid Massaad and C. G. Allen},
  journal={Diabetes, obesity & metabolism},
  year={2007},
  volume={9 4},
  pages={
          575-84
        }
}
AIM This randomized, double-blind study evaluated the efficacy of switching from atorvastatin (ATV) 10 mg to ezetimibe/simvastatin (EZE/SIMVA) 10/20 mg, EZE/SIMVA 10/40 mg or doubling the dose of ATV from 10 to 20 mg in patients with type 2 diabetes (T2D). METHODS Eligible patients had haemoglobin A(1C)< or =10%, were aged > or =18 years and were on ATV 10 mg for > or =6 weeks before study entry. After a 4-week open-label ATV 10 mg run-in, patients were randomized to EZE/SIMVA 10/20 mg (n… CONTINUE READING
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