Efficacy of early intensive rosuvastatin therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (ROSEMARY Study).

@article{Ko2014EfficacyOE,
  title={Efficacy of early intensive rosuvastatin therapy in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (ROSEMARY Study).},
  author={Young Guk Ko and Hoyoun Won and Dong Ho Shin and Jung-sun Kim and Byeong Keuk Kim and Donghoon Choi and Myeong Ki Hong and Jang-Ho Bae and Sahng Ha Lee and Do Sun Lim and Yangsoo Jang},
  journal={The American journal of cardiology},
  year={2014},
  volume={114 1},
  pages={29-35}
}
The purpose of the study was to investigate whether early high-dose potent statin therapy in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention can reduce infarct size compared with conventional low-dose statin therapy. In a randomized placebo-controlled multicenter trial, 185 patients were assigned either to an early high-dose rosuvastatin group (n = 92, rosuvastatin 40 mg before treatment plus maintenance for 7 days) or to a conventional low… CONTINUE READING
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