Efficacy of dexmedetomidine in prevention of junctional ectopic tachycardia and acute kidney injury after pediatric cardiac surgery: A meta‐analysis

@article{Li2018EfficacyOD,
  title={Efficacy of dexmedetomidine in prevention of junctional ectopic tachycardia and acute kidney injury after pediatric cardiac surgery: A meta‐analysis},
  author={Xin Li and Chengxin Zhang and Di Dai and Haiyuan Liu and Shenglin Ge},
  journal={Congenital Heart Disease},
  year={2018},
  volume={13},
  pages={799–807}
}
OBJECTIVE We conducted a meta-analysis to evaluate the effects of prophylactic perioperative dexmedetomidine administration on postoperative junctional ectopic tachycardia (JET) and acute kidney injury (AKI) in pediatric patients having undergone cardiac surgery. DESIGN This systematic review was registered with PROSPERO (CRD42017083880). Databases including PubMed, Cochrane Central Register of Controlled Trials, and Web of Science were searched for randomized controlled trials (RCTs) and… Expand

Paper Mentions

Interventional Clinical Trial
Aim 1: Primary Prevention of Post-operative Cardiac Arrhythmias 1. To evaluate the efficacy of dexmedetomidine vs. the combination of Magnesium Sulfate and… Expand
ConditionsCardiac; Dysrhythmia, Postoperative, Congenital Heart Surgery
InterventionDrug
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Big Syringe, Little Syringe.

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Perioperative administration of dexmedetomidine in adult patients undergoing cardiac surgery may reduce the incidence of postoperative AKI and future trials are needed to determine the dose and timing in improving outcomes, especially in patients with decreased baseline kidney function. Expand
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