Efficacy of dalbavancin against methicillin-resistant Staphylococcus aureus in the rat granuloma pouch infection model.

@article{Jabs2004EfficacyOD,
  title={Efficacy of dalbavancin against methicillin-resistant Staphylococcus aureus in the rat granuloma pouch infection model.},
  author={Daniela Jab{\'e}s and Gianpaolo Candiani and Gabriella M Romano and Cristina Brunati and Simona Riva and Marco Cavaleri},
  journal={Antimicrobial agents and chemotherapy},
  year={2004},
  volume={48 4},
  pages={1118-23}
}
Infections due to methicillin-resistant Staphylococcus aureus (MRSA) are an important cause of morbidity and mortality in hospital patients. Moreover, increased incidences of outpatient MRSA have been recently reported. This study investigated the bactericidal activity of dalbavancin, a novel, semisynthetic glycopeptide antibiotic, against methicillin-sensitive S. aureus (MSSA) and MRSA in the rat granuloma pouch infection model. A single intravenous dose of 10 mg of dalbavancin/kg of body… CONTINUE READING