Efficacy of combined treatment with growth hormone and gonadotropin releasing hormone analogue in children with poor prognosis of adult height.

@article{Toumba2007EfficacyOC,
  title={Efficacy of combined treatment with growth hormone and gonadotropin releasing hormone analogue in children with poor prognosis of adult height.},
  author={Meropi Toumba and Ioanna Bacopoulou and Savvas C. Savva and Nicos Skordis},
  journal={Indian pediatrics},
  year={2007},
  volume={44 7},
  pages={
          497-502
        }
}
OBJECTIVE This study was conducted to study the role of combination therapy of growth hormone and Gonadotropin-releasing hormone (GnRH) analogues in girls with idiopathic central precocious puberty (CPP) or idiopathic short stature (ISS). METHODS Five girls with CPP (median age 9.1 y, pubertal stage 2-3) (3 of them previously treated with GnRH analogue (GnRHa) for 16.2 +/- 0.3 months) and 8 girls with ISS (median age 11.4 y, pubertal stage 2-3) (previously treated with GH for 10.95 +/- 1.42… CONTINUE READING

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