Efficacy of combined atorvastatin and sildenafil in promoting recovery after ischemic stroke in mice.

Abstract

OBJECTIVE The aim of this study was to test the hypothesis that a combination of atorvastatin and sildenafil promotes recovery in an additive manner after ischemic stroke in mice. DESIGN Adult C57BL/6 mice (n = 67) were subjected to transient middle cerebral artery occlusion. Vehicle-control (H2O), atorvastatin (0.3 mg/kg), sildenafil (0.3 mg/kg), or… (More)
DOI: 10.1097/PHM.0b013e3182643f1a

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