Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial

@article{Sndor2005EfficacyOC,
  title={Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial},
  author={P. S{\'a}ndor and L. Di Clemente and G. Coppola and U. Saenger and A. Fumal and D. Magis and L. Seidel and R. Agosti and J. Schoenen},
  journal={Neurology},
  year={2005},
  volume={64},
  pages={713 - 715}
}
Riboflavin, which improves energy metabolism similarly to coenzyme Q10 (CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3 × 100 mg/day) and placebo in 42 migraine patients in a double-blind, randomized, placebo-controlled trial. CoQ10 was superior to placebo for attack-frequency, headache-days and days-with-nausea in the third treatment month and well tolerated; 50%-responder-rate for attack frequency was 14.4% for placebo and 47.6% for CoQ10 (number-needed-to-treat: 3). CoQ10… Expand
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