Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of major depressive disorder with high levels of anxiety (anxious depression): a pooled analysis of 10 studies.
@article{Papakostas2008EfficacyOB, title={Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of major depressive disorder with high levels of anxiety (anxious depression): a pooled analysis of 10 studies.}, author={G. Papakostas and S. Stahl and A. Krishen and C. A. Seifert and V. Tucker and E. P. Goodale and M. Fava}, journal={The Journal of clinical psychiatry}, year={2008}, volume={69 8}, pages={ 1287-92 } }
OBJECTIVE
The goal of this work was to compare the efficacy of the norepinephrine and dopamine reuptake inhibitor bupropion with the selective serotonin reuptake inhibitors (SSRIs) in the treatment of major depressive disorder with high levels of anxiety (anxious depression).
METHOD
Ten double-blind, randomized studies from 1991 through 2006 were combined (N = 2122). Anxious depression was defined as a 17-item Hamilton Rating Scale for Depression (HAM-D-17) anxiety-somatization factor score… CONTINUE READING
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References
SHOWING 1-10 OF 42 REFERENCES
Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of anxiety symptoms in major depressive disorder: a meta-analysis of individual patient data from 10 double-blind, randomized clinical trials.
- Psychology, Medicine
- Journal of psychiatric research
- 2008
- 36
Resolution of Sleepiness and Fatigue in Major Depressive Disorder: A Comparison of Bupropion and the Selective Serotonin Reuptake Inhibitors
- Psychology, Medicine
- Biological Psychiatry
- 2006
- 116
Response of anxiety and agitation symptoms during nefazodone treatment of major depression.
- Psychology, Medicine
- The Journal of clinical psychiatry
- 1995
- 85
Bupropion sustained release versus paroxetine for the treatment of depression in the elderly.
- Psychology, Medicine
- The Journal of clinical psychiatry
- 2000
- 145
Remission rates following antidepressant therapy with bupropion or selective serotonin reuptake inhibitors: a meta-analysis of original data from 7 randomized controlled trials.
- Psychology, Medicine
- The Journal of clinical psychiatry
- 2005
- 282
Fluoxetine, placebo, and tricyclic antidepressants in major depression with and without anxious features.
- Psychology, Medicine
- The Journal of clinical psychiatry
- 1994
- 127
Does pretreatment anxiety predict response to either bupropion SR or sertraline?
- Psychology, Medicine
- Journal of affective disorders
- 2001
- 28
- Highly Influential
Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.
- Medicine
- The New England journal of medicine
- 2006
- 840
- PDF
Response in Relation to Baseline Anxiety Levels in Major Depressive Disorder Treated with Bupropion Sustained Release or Sertraline
- Psychology, Medicine
- Neuropsychopharmacology
- 2001
- 52
- Highly Influential
- PDF
A double-blind comparison of sertraline and clomipramine in the treatment of major depressive disorder and associated anxiety in general practice
- Psychology, Medicine
- Journal of psychopharmacology
- 1994
- 33