Efficacy of botulinum toxin A for treatment of upper esophageal sphincter dysfunction.

@article{Alberty2000EfficacyOB,
  title={Efficacy of botulinum toxin A for treatment of upper esophageal sphincter dysfunction.},
  author={Juergen Alberty and Michael Oelerich and Kaja Ludwig and Susanne Hartmann and Wolfgang Stoll},
  journal={The Laryngoscope},
  year={2000},
  volume={110 7},
  pages={1151-6}
}
OBJECTIVES To investigate the efficacy of botulinum toxin A (BTA)-induced chemodenervation of the upper esophageal sphincter (UES) in patients with dysphagia and UES dysfunction. STUDY DESIGN Prospective clinical trial in 10 selected patients with pure UES dysfunction. METHODS In each patient 30 units of BTA were injected into the UES under brief general anesthesia. Videofluoroscopic swallowing study (VSS) was done and a clinical symptom score was determined before and after treatment… CONTINUE READING

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