Efficacy of bioabsorbable antibiotic containing bone screw in the prevention of biomaterial-related infection due to Staphylococcus aureus.

@article{Mkinen2005EfficacyOB,
  title={Efficacy of bioabsorbable antibiotic containing bone screw in the prevention of biomaterial-related infection due to Staphylococcus aureus.},
  author={Tatu Johannes M{\"a}kinen and Minna Veiranto and Juhani Knuuti and J. P. Jalava and Pertti T{\"o}rm{\"a}l{\"a} and Hannu T. Aro},
  journal={Bone},
  year={2005},
  volume={36 2},
  pages={292-9}
}
Impregnation of antimicrobial agents within biodegradable orthopedic implants provides a possibility for local antimicrobial prophylaxis of biomaterial-related infections. The objective of this study was to evaluate the efficacy of a bioabsorbable ciprofloxacin containing bone screw (Ab-PLGA) in the prevention of biomaterial-related infection due to Staphylococcus aureus in a rabbit model. Animals in Group I (n=8) received a Ab-PLGA screw contaminated with S. aureus, while animals in Group II… CONTINUE READING
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