Efficacy of atorvastatin compared with simvastatin in patients with hypercholesterolemia.

@article{Farnier2000EfficacyOA,
  title={Efficacy of atorvastatin compared with simvastatin in patients with hypercholesterolemia.},
  author={Michel Farnier and J J Portal and Pascal Maigret},
  journal={Journal of cardiovascular pharmacology and therapeutics},
  year={2000},
  volume={5 1},
  pages={27-32}
}
BACKGROUND Atorvastatin, a new enantiomerically pure synthetic statin, has shown a marked low-density lipoprotein (LDL) cholesterol reduction at doses ranging from 10 to 80 mg/d. This trial was designed to compare the efficacy of atorvastatin 10 mg with simvastatin 10 mg and 20 mg, the latter dose being commonly used in some countries. METHODS AND RESULTS A parallel group, randomized, PROBE, multicenter study was conducted to compare the efficacy of 10 mg/d atorvastatin with that of 10 mg/d… CONTINUE READING

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