Efficacy of ascorbic acid, N-acetylcysteine, or combination of both on top of saline hydration versus saline hydration alone on prevention of contrast-Induced nephropathy: a prospective randomized study.

@article{Albabtain2013EfficacyOA,
  title={Efficacy of ascorbic acid, N-acetylcysteine, or combination of both on top of saline hydration versus saline hydration alone on prevention of contrast-Induced nephropathy: a prospective randomized study.},
  author={Monirah A Albabtain and Ali A Almasood and Hytham Alshurafah and Hussain Alamri and Hani M. Tamim},
  journal={Journal of interventional cardiology},
  year={2013},
  volume={26 1},
  pages={90-6}
}
BACKGROUND Antioxidant drugs such as N-acetylcysteine (NAC) and ascorbic acid have been evaluated in interventional studies to prevent contrast-induced nephropathy (CIN), however, there are limited data on comparing either or both, with background of standard intravenous saline hydration versus the standard intravenous saline hydration alone in preventing CIN. METHODS We conducted a single-center randomized trial among patients undergoing coronary angiography or percutaneous coronary… CONTINUE READING

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