Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species.

@article{Newcomer2012EfficacyOA,
  title={Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species.},
  author={Benjamin W. Newcomer and Mylissa S D Marley and Julia F. Ridpath and John D. Neill and David W Boykin and Arvind Kumar and M. Daniel Givens},
  journal={Antiviral research},
  year={2012},
  volume={96 2},
  pages={127-9}
}
Pestiviruses are economically important pathogens of livestock. An aromatic cationic compound (DB772) has previously been shown to inhibit bovine viral diarrhea virus (BVDV) type 1 in vitro at concentrations lacking cytotoxic side effects. The aim of this study was to determine the scope of antiviral activity of DB772 among diverse pestiviruses. Isolates of BVDV 2, border disease virus (BDV), HoBi virus, pronghorn virus and Bungowannah virus were tested for in vitro susceptibility to DB772 by… CONTINUE READING

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