Efficacy of alkalinized lidocaine for reducing pain on intravenous and epidural catheterization

Purpose. To investigate whether increasing the pH of lidocaine could reduce the pain caused by its skin infiltration as well as that caused by intravenous and epidural needle insertion. Methods. A randomized, double-blind trial was undertaken in patients who were allocated to receive topical anesthesia with either plain (plain group; n = 25) or alkalinized… CONTINUE READING