Efficacy of adjuvant aromatase inhibitor in hormone receptor-positive postmenopausal breast cancer patients according to the body mass index

@inproceedings{endur2012EfficacyOA,
  title={Efficacy of adjuvant aromatase inhibitor in hormone receptor-positive postmenopausal breast cancer patients according to the body mass index},
  author={Mehmet Ali Nahit Şendur and Selim Aksoy and Nurullah Zengin and Kadri Altundag},
  booktitle={British Journal of Cancer},
  year={2012}
}
Background:Increased adiposity may trigger signalling pathways that induce aromatase expression. As aromatase inhibitors exert their effects by blocking the aromatase enzyme, higher body mass index (BMI) can reduce the effect of aromatase inhibitors. Thus, we aimed to investigate retrospectively the effect of BMI on the efficacy of aromatase inhibitors in hormone receptor-positive postmenopausal patients with breast cancer.Methods:Newly diagnosed hormone receptor-positive breast cancer patients… CONTINUE READING

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