Efficacy of a specific polyclonal equine F(ab')2 against avian influenza (H5N1) in ferrets: synergy with oseltamivir.

Abstract

AIM Current therapies against avian influenza (H5N1) provide limited clinical benefit. FBF-001 is a highly purified equine polyclonal immunoglobulin fragment against H5N1. METHODS Using a ferret model of severe acute H5N1 infection, we assessed FBF-001 when administered on the same day or 1 day after viral challenge, in comparison with oseltamivir therapy… (More)
DOI: 10.2217/imt-2016-0062

Topics

Cite this paper

@article{Herbreteau2016EfficacyOA, title={Efficacy of a specific polyclonal equine F(ab')2 against avian influenza (H5N1) in ferrets: synergy with oseltamivir.}, author={C{\'e}cile H{\'e}l{\`e}ne Herbreteau and M{\'e}lanie Denizot and Suzanne Lowther and Sarah Riddell and L. Frazer and Jessica Haining and Rachel Arkinstall and Jean Payne and Jenni Harper and Dayna A. Johnson and Ana{\"i}s Pasquier and D Middleton and J. A. Saluzzo}, journal={Immunotherapy}, year={2016}, volume={8 9}, pages={1021-32} }