• Corpus ID: 8299952

Efficacy of a soy moisturizer in photoaging: a double-blind, vehicle-controlled, 12-week study.

  title={Efficacy of a soy moisturizer in photoaging: a double-blind, vehicle-controlled, 12-week study.},
  author={Warren Wallo and Judith Nebus and James J. Leyden},
  journal={Journal of drugs in dermatology : JDD},
  volume={6 9},
Serine protease inhibitors (soybean trypsin inhibitor [STI] and Bowman-Birk protease inhibitor [BBI]) found in soybeans have been shown to inhibit melanosome phagocytosis by keratinocytes via protease-activated receptor 2 (PAR-2). Pre-clinical studies have confirmed the skin lightening potential of these molecules. In this study, we investigated the efficacy of a novel soy moisturizer containing nondenaturated STI and BBI for the improvement of skin tone, pigmentation, and other photoaging… 

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