Efficacy of a new low-dose oral contraceptive with drospirenone in premenstrual dysphoric disorder.

  title={Efficacy of a new low-dose oral contraceptive with drospirenone in premenstrual dysphoric disorder.},
  author={Kimberly Ann Yonkers and Candace Brown and Teri B. Pearlstein and Marie Foegh and Carole Sampson-Landers and Andrea J. Rapkin},
  journal={Obstetrics and gynecology},
  volume={106 3},
OBJECTIVE To compare the efficacy of a new low-dose oral contraceptive pill (OCP) formulation with placebo in reducing symptoms of premenstrual dysphoric disorder. METHODS This multicenter, double-blind, randomized clinical trial consisted of 2 run-in and 3 treatment cycles with daily symptom charting; 450 women with symptoms of premenstrual dysphoric disorder were randomized to either placebo or an OCP formulation containing drospirenone 3 mg and ethinyl estradiol 20 microg. Hormones were… CONTINUE READING
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