Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin.

@article{Kubena1990EfficacyOA,
  title={Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and T-2 toxin.},
  author={Leon F. Kubena and Roger B. Harvey and William E. Huff and Donald E. Corrier and Timothy D. Phillips and George Edwin Rottinghaus},
  journal={Poultry science},
  year={1990},
  volume={69 7},
  pages={
          1078-86
        }
}
A hydrated sodium calcium aluminosilicate (HSCAS) was incorporated into diets (.5%) containing 3.5 mg of aflatoxin (AF) per kg and 8.0 mg of T-2 toxin (T-2) per kg, singly, and in combination. Male broiler chicks (n = 480) were provided with feed and water for ad libitum consumption from 1 to 21 days of age. Body weight gains were significantly depressed by AF and T-2, singly, and further decreased by the combination of the two toxins. Efficiency of feed utilization was not affected. The AF… 
Efficacy of a hydrated sodium calcium aluminosilicate to reduce the toxicity of aflatoxin and diacetoxyscirpenol.
TLDR
It is indicated that HSCAS can diminish the adverse effects of AF but not of DAS, and almost totalprotection against the effects caused by AF alone, limited protection against the combination, but no Protection against the DAS alone.
Effects of a hydrated sodium calcium aluminosilicate (T-Bind) on mycotoxicosis in young broiler chickens.
TLDR
It is demonstrated that this specific sorbent can provide protection against the toxicity of AF, but not T-2 toxin, in young broiler chicks.
Efficacy of hydrated sodium calcium aluminosilicate to reduce the individual and combined toxicity of aflatoxin and ochratoxin A.
TLDR
The HSCAS reduced theoxicity of aflatoxin, but had little effect on either the toxicity of ochratoxin A alone or the toxicity resulting from the combination of a Flatoxin and ochRatoxin A.
Effects of a hydrated sodium calcium aluminosilicate on growing turkey poults during aflatoxicosis.
TLDR
Findings indicate that HSCAS may diminish many of the adverse effects of AF in an AF-sensitive species, the turkey.
Effect of hydrated sodium calcium aluminosilicates on aflatoxicosis in broiler chicks.
TLDR
It is demonstrated that these specific HSCAS compounds can be protective against the effects of AF in young growing broilers and further emphasizes the fact that all silicate-type sorbents are not equal in their ability to protect against aflatoxicosis.
Efficacy of a hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks.
TLDR
Improved Milbond-TX dramatically reduced the incidence and severity of the hepatic histopathology changes associated with aflatoxicosis and completely prevented the renal lesions of a Flatoxicosis.
Efficiency of hydrated sodium calcium aluminosilicate to ameliorate the adverse effects of graded levels of aflatoxin B1 in broiler chicks.
TLDR
Results from this study indicate that dietary supplementation with HSCAS can effectively improve BW gain and partially ameliorate aflatoxicosis for broiler chicks fed AFB1-contaminated feeds.
Influence of a hydrated sodium calcium aluminosilicate and virginiamycin on aflatoxicosis in broiler chicks.
TLDR
HSCAS and HSCAS+VM can counteract some of the toxic effects of AF in growing broiler chicks, suggesting approximately 75% protection against decreased BW gain by H SCAS and 87% protection by the HSCas+VM combination.
Efficacy of different adsorbents in reducing the toxic effects of aflatoxin B1 in broiler diets
The ability of dietary hydrated sodium calcium aluminosilicate (HSCAS), diatomite and activated charcoal (AC) in reducing the detrimental effects of aflatoxin B1 (AFB1) in broiler diets was
Efficacy of N-Acetylcysteine and Hydrated Sodium Calcium Aluminosilicate to Reduce the Effects of Aflatoxin B1 Intoxication in Broiler Chickens
This study was designed to evaluate the efficacy of N-acetylcysteine (NAC) and / or Hydrated Sodium Calcium Aluminosilicate (HSCAS) to counteract the toxic effects of aflatoxin AFB1 in broiler
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References

SHOWING 1-10 OF 26 REFERENCES
Prevention of aflatoxicosis by addition of hydrated sodium calcium aluminosilicate to the diets of growing barrows.
Hydrated sodium calcium aluminosilicate (HSCAS), an anticaking agent for mixed feed, was added to the diets of growing barrows and was evaluated for its potential to ameliorate the clinical signs of
Toxic synergism between aflatoxin and T-2 toxin in broiler chickens.
TLDR
Data indicate that aflatoxin and T-2 toxin can interact to produce synergistic toxicity and this synergism is a threat to poultry production due to the prevalence of these mycotoxins and severity of the interactive toxicity of theseMycotoxin.
Diminution of aflatoxicosis in growing chickens by the dietary addition of a hydrated, sodium calcium aluminosilicate.
TLDR
It is suggested that HSCAS can modulate the toxicity of AFB1 and AF in the chicken; however, adding activated charcoal to the diet did not appear to have protective properties against the effects of aflatoxin B1 or of a flatoxin.
Influence of ochratoxin A and T-2 toxin singly and in combination on broiler chickens.
TLDR
The data indicate that OA and T-2 in combination may be more toxic for some parameters than the individual mycotoxins, and may pose a greater problem for the poultry industry than either of the mycotoxin individually.
Individual and combined toxicity of deoxynivalenol and T-2 toxin in broiler chicks.
TLDR
Several parameters not altered by DON or T-2 toxin singly were significantly affected by the combination, indicating that the combination may pose a potentially greater problem to the poultry industry than either of the mycotoxins individually.
Mycotoxicosis Caused by Either T-2 Toxin or Diacetoxyscirpenol in the Diet of Broiler Chickens
TLDR
Seven-day-old male broiler chickens were fed either T-2 toxin or diacetoxyscirpenol at 4 and 16 ppm for 21 days and had reductions of feed consumption and of weight gain and had necrotic tissues in dead chickens, which had atrophied lymphoid organs and were anemic.
Hydrated sodium calcium aluminosilicate: a high affinity sorbent for aflatoxin.
TLDR
The HSCAS, when added to the diet of Leghorn and broiler chicks at a level of .5%, significantly diminished the adverse effects of feeding 7.5 mg AFB1/kg of feed, suggesting this agent (and other aluminosilicate congeners) may prove effective in the preventive management of aflatoxicosis.
Progression of aflatoxicosis in broiler chickens.
TLDR
Liver atrophy was indicated in the early stages of aflatoxicosis by a decrease in the relative weight of this organ and hepatomegaly became apparent due to lipid accumulation in the liver as a flatoxicosis progressed.
Experimental induction of chronic aflatoxicosis in chickens by purified aflatoxin B1 and its reversal by activated charcoal, phenobarbital, and reduced glutathione.
TLDR
The results indicate that the simultaneous presence of these agents with AFB1 considerably prevented the inhibitory effect of AFB1 on the microsomal cytochrome P-450 and benzphetamine N-demethylase activity and these agents were able to provide moderate protection against AFB1-induced liver injury manifested by elevation of SGOT activity.
Impairment of coagulation function during aflatoxicosis in young chickens.
TLDR
The data suggest that severe impairment of extrinsic and common clotting pathway functions occurs during aflatoxicosis in the chicken and that prothrombin is primarily affected during this coagulopathy.
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