Efficacy of a hepatitis C virus core antigen enzyme-linked immunosorbent assay for the identification of 'window-phase' blood donations.

@article{Lee2001EfficacyOA,
  title={Efficacy of a hepatitis C virus core antigen enzyme-linked immunosorbent assay for the identification of 'window-phase' blood donations.},
  author={Stephen S. Lee and Julie Longua Peterson and P. C. Niven and Chander Bahl and E Eugene Page and R Deleys and D Giordano-Schmidt and Dorris H Baggett and George H. Green},
  journal={Vox sanguinis},
  year={2001},
  volume={80 1},
  pages={19-23}
}
BACKGROUND AND OBJECTIVES Recent studies have suggested that potentially infectious donations provided during the antibody-negative 'window' phase of hepatitis C virus (HCV) infection may be identified by testing for viral RNA or HCV core protein. We therefore evaluated the performance of an HCV antigen enzyme-linked immunosorbent assay (ELISA) for identification of window-phase donations and for prospective screening of blood donors. MATERIALS AND METHODS One-hundred and twenty-eight… CONTINUE READING

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