Efficacy of a Six-Month versus a 36-Month Regimen for Prevention of Tuberculosis in HIV-Infected Persons in India: A Randomized Clinical Trial

@inproceedings{Swaminathan2012EfficacyOA,
  title={Efficacy of a Six-Month versus a 36-Month Regimen for Prevention of Tuberculosis in HIV-Infected Persons in India: A Randomized Clinical Trial},
  author={S. S. Swaminathan and Pradeep Aravindan Menon and Narendran Gopalan and Venkatesan Perumal and Ramesh Kumar Santhanakrishnan and Ranjani Ramachandran and Ponnuraja Chinnaiyan and Sheik Iliayas and Padmapriyadarsini Chandrasekaran and Pooranaganga Devi Navaneethapandian and Thiruvalluvan Elangovan and Mai Tuyet Pho and Fraser Wares and Narayanan Paranji RamaIyengar},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The optimal duration of preventive therapy for tuberculosis (TB) among HIV-infected persons in TB-endemic countries is unknown. METHODS An open-label randomized clinical trial was performed and analyzed for equivalence. Seven hundred and twelve HIV-infected, ART-naïve patients without active TB were randomized to receive either ethambutol 800 mg and isoniazid 300 mg daily for six-months (6EH) or isoniazid 300 mg daily for 36-months (36H). Drugs were dispensed fortnightly and… CONTINUE READING
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Efficacy of a 6 month vs a 36 month regimen for prevention of TB among HIV-infected persons in India: a randomized clinical trial

  • S Swaminathan, PA Menon, V Perumal, R Santhanakrishnan, R Ramachandran
  • In Program and abstracts of Conference on…
  • 2010
1 Excerpt

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