Efficacy of a 24-week course of PEG-interferon alpha-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance.

@article{Santantonio2005EfficacyOA,
  title={Efficacy of a 24-week course of PEG-interferon alpha-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance.},
  author={Teresa Santantonio and Massimo Fasano and Emanuele Sinisi and Angela Guastadisegni and Caterina Casalino and Michele Mazzola and Ruggiero Francavilla and Giuseppe Pastore},
  journal={Journal of hepatology},
  year={2005},
  volume={42 3},
  pages={329-33}
}
BACKGROUND/AIMS Interferon (IFN) monotherapy significantly reduces the chronicity rate of acute hepatitis C (AHC) but optimal regimen and treatment timing remain undefined. The aim of this study was to assess the efficacy of a 6-month course of pegylated IFN (PEG-IFN) alpha-2b monotherapy in AHC patients and to investigate if IFN treatment initiated after 12 weeks from clinical presentation, still achieved a high response rate. METHODS Sixteen AHC patients still viremic after 12 weeks from… CONTINUE READING
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