Efficacy of Treatment for Somatoform Disorders: A Review of Randomized Controlled Trials

  title={Efficacy of Treatment for Somatoform Disorders: A Review of Randomized Controlled Trials},
  author={Kurt Kroenke},
  journal={Psychosomatic Medicine},
  • K. Kroenke
  • Published 1 November 2007
  • Medicine, Psychology
  • Psychosomatic Medicine
Objective: To review the evidence from randomized clinical trials (RCTs) that have focused on the treatment of patients with Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) somatoform disorders. Although somatoform disorders are among the most common mental disorders presenting in the general medical setting, the strength of evidence for specific treatments has not been well synthesized. Methods: MEDLINE search of articles published in English from 1966 to 2006… 
Effectiveness of psychotherapy for severe somatoform disorder: meta-analysis.
Overall findings suggest that psychotherapy is effective in severe somatoform disorder, and future randomised controlled studies should examine specific interventions and mechanisms of change.
Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults.
The effects of non-pharmacological interventions for somatoform disorders and MUPS in adults, in comparison with treatment as usual, waiting list controls, attention placebo, psychological placebo, enhanced or structured care, and other psychological or physical therapies are assessed.
Effectiveness of Group Versus Individual Cognitive-Behavioral Therapy in Patients With Abridged Somatization Disorder: A Randomized Controlled Trial
CBT in individual and group settings results in significant improvements in somatic symptoms among patients with somatoform abridged disorder compared with TAU, and individual CBT results in greater posttreatment improvements at 6-month and 12-month follow-ups.
Treatment course and its predictors in patients with somatoform disorders: A routine outcome monitoring study in secondary psychiatric care.
Primary psychiatric care outpatients with somatoform disorders showed high co-morbidity with anxiety and mood disorders, and an unfavourable 6-month course of both symptoms and functioning.
Somatic Symptom Disorder.
The main feature of this disorder is a patient's concern with physical symptoms that he or she attributes to a nonpsychiatric disease.
Effectiveness of a Multimodal Treatment Program for Somatoform Pain Disorder
Compared with previous data with small to moderate effect sizes, a multimodal program seems to be more effective than other interventions to address somatoform pain disorder.
Cognitive Behavioral Therapy Versus Progressive Muscle Relaxation Training for Multiple Somatoform Symptoms: Results of a Randomized Controlled Trial
Although unexplained multiple symptoms and somatoform disorders are a highly prevalent condition in primary practice, few randomized controlled trials of cognitive behavioral therapy (CBT) have been
Somatoform disorders in patients with chronic pain
It is confirmed that somatoform disorders are common co-morbid diagnoses in patients with chronic pain and combining psychological treatments with medication, appropriate physical treatments and attending to social issues, may indeed improve the well-being of such patients.


Cognitive-Behavioral Therapy for Somatization and Symptom Syndromes: A Critical Review of Controlled Clinical Trials
CBT can be an effective treatment for patients with somatization or symptom syndromes and benefits can occur whether or not psychological distress is ameliorated.
Cognitive-behavioral therapy for somatization disorder: a randomized controlled trial.
For patients diagnosed as having SD, CBT may produce clinical benefits beyond those that result from the current state-of-the-art treatment and a greater decrease in health care costs.
Treatment of Somatoform Disorders With St. John's Wort: A Randomized, Double-Blind and Placebo-Controlled Trial
Administration of 600 mg of SJW extract LI 160 daily is effective and safe in the treatment of somatoform disorders, thereby confirming results from a previous study.
Behavioral medicine approaches to somatoform disorders.
Randomized controlled studies support the efficacy of individual and group CBT for the treatment of hypochondriasis, body dysmorphic disorder (BDD), and undifferentiated somatoform disorders including medically unexplained symptoms, chronic fatigue syndrome, and noncardiac chest pain.
Multisomatoform disorder. An alternative to undifferentiated somatoform disorder for the somatizing patient in primary care.
Multisomatoform disorder may be a valid diagnosis and potentially more useful than the DSM-IV diagnosis of undifferentiated somatization disorder and its diagnosis should not be precluded simply because of a coexisting mood or anxiety disorder.
Opipramol for the treatment of somatoform disorders results from a placebo-controlled trial
A Randomized Clinical Trial of a Care Recommendation Letter Intervention for Somatization in Primary Care
The CR letter has a favorable impact on physical impairment of primary care patients with MSD, especially for patients with comorbid chronic physical disease.
Medically Unexplained Physical Symptoms, Anxiety, and Depression: A Meta‐Analytic Review
Meta‐analytic integration confirms that the four functional somatic syndromes (IBS, NUD, FM, CFS) are related to (but not fully dependent on) depression and anxiety.
A randomized placebo-controlled trial of fluoxetine in body dysmorphic disorder.
Fluoxetine is safe and more effective than placebo in delusional and nondelusional patients with BDD and the presence of major depression, obsessive-compulsive disorder, or a personality disorder.