Efficacy of Treatment for Somatoform Disorders: A Review of Randomized Controlled Trials

  title={Efficacy of Treatment for Somatoform Disorders: A Review of Randomized Controlled Trials},
  author={Kurt Kroenke},
  journal={Psychosomatic Medicine},
  • K. Kroenke
  • Published 1 November 2007
  • Medicine, Psychology
  • Psychosomatic Medicine
Objective: To review the evidence from randomized clinical trials (RCTs) that have focused on the treatment of patients with Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV) somatoform disorders. Although somatoform disorders are among the most common mental disorders presenting in the general medical setting, the strength of evidence for specific treatments has not been well synthesized. Methods: MEDLINE search of articles published in English from 1966 to 2006… 
Pharmacological interventions for somatoform disorders in adults.
A systematic review and meta-analysis of placebo-controlled studies examined the efficacy and tolerability of different types of antidepressants, the combination of an antidepressant and an antipsychotic, antipsychotics alone, or natural products in adults with somatoform disorders in adults to improve optimal treatment decisions.
Effectiveness of psychotherapy for severe somatoform disorder: meta-analysis.
Overall findings suggest that psychotherapy is effective in severe somatoform disorder, and future randomised controlled studies should examine specific interventions and mechanisms of change.
Non-pharmacological interventions for somatoform disorders and medically unexplained physical symptoms (MUPS) in adults.
The effects of non-pharmacological interventions for somatoform disorders and MUPS in adults, in comparison with treatment as usual, waiting list controls, attention placebo, psychological placebo, enhanced or structured care, and other psychological or physical therapies are assessed.
Effectiveness of Group Versus Individual Cognitive-Behavioral Therapy in Patients With Abridged Somatization Disorder: A Randomized Controlled Trial
CBT in individual and group settings results in significant improvements in somatic symptoms among patients with somatoform abridged disorder compared with TAU, and individual CBT results in greater posttreatment improvements at 6-month and 12-month follow-ups.
Treatment course and its predictors in patients with somatoform disorders: A routine outcome monitoring study in secondary psychiatric care.
Primary psychiatric care outpatients with somatoform disorders showed high co-morbidity with anxiety and mood disorders, and an unfavourable 6-month course of both symptoms and functioning.
Cognitive behavioral therapy for somatoform disorders.
Somatic Symptom Disorder.
The main feature of this disorder is a patient's concern with physical symptoms that he or she attributes to a nonpsychiatric disease.
Effectiveness of a Multimodal Treatment Program for Somatoform Pain Disorder
Compared with previous data with small to moderate effect sizes, a multimodal program seems to be more effective than other interventions to address somatoform pain disorder.


Cognitive-Behavioral Therapy for Somatization and Symptom Syndromes: A Critical Review of Controlled Clinical Trials
CBT can be an effective treatment for patients with somatization or symptom syndromes and benefits can occur whether or not psychological distress is ameliorated.
Cognitive-behavioral therapy for somatization disorder: a randomized controlled trial.
For patients diagnosed as having SD, CBT may produce clinical benefits beyond those that result from the current state-of-the-art treatment and a greater decrease in health care costs.
Antidepressant therapy for unexplained symptoms and symptom syndromes.
Antidepressants can be effective for various physical symptoms and symptom syndromes and onbivariate tally tricyclic studies were associated with a greater likelihood of efficacy than SSRI studies.
Treatment of Somatoform Disorders With St. John's Wort: A Randomized, Double-Blind and Placebo-Controlled Trial
Administration of 600 mg of SJW extract LI 160 daily is effective and safe in the treatment of somatoform disorders, thereby confirming results from a previous study.
Behavioral medicine approaches to somatoform disorders.
Randomized controlled studies support the efficacy of individual and group CBT for the treatment of hypochondriasis, body dysmorphic disorder (BDD), and undifferentiated somatoform disorders including medically unexplained symptoms, chronic fatigue syndrome, and noncardiac chest pain.
A trial of the effect of a standardized psychiatric consultation on health outcomes and costs in somatizing patients.
Somatizing patients with a lifetime history of six to 12 unexplained physical symptoms reported better physical functioning after their primary care physician was provided appropriate treatment recommendations via a psychiatric consultation, which reduces subsequent charges for medical care, while improving health outcomes in a chronically impaired population.
Multisomatoform disorder. An alternative to undifferentiated somatoform disorder for the somatizing patient in primary care.
Multisomatoform disorder may be a valid diagnosis and potentially more useful than the DSM-IV diagnosis of undifferentiated somatization disorder and its diagnosis should not be precluded simply because of a coexisting mood or anxiety disorder.
Opipramol for the treatment of somatoform disorders results from a placebo-controlled trial
Somatoform disorders in general practice Prevalence , functional impairment and comorbidity with anxiety and depressive disorders
  • 2004
A Randomized Clinical Trial of a Care Recommendation Letter Intervention for Somatization in Primary Care
The CR letter has a favorable impact on physical impairment of primary care patients with MSD, especially for patients with comorbid chronic physical disease.