Efficacy of Synthetic Peptide-Containing Surfactant in the Treatment of Respiratory Distress Syndrome in Preterm Infant Rhesus Monkeys

@article{Revak1996EfficacyOS,
  title={Efficacy of Synthetic Peptide-Containing Surfactant in the Treatment of Respiratory Distress Syndrome in Preterm Infant Rhesus Monkeys},
  author={Susan D. Revak and Thurman A Merritt and Charles G. Cochrane and Gregory P. Heldt and Monica S Alberts and David W Anderson and Ahmed Kheiter},
  journal={Pediatric Research},
  year={1996},
  volume={39},
  pages={715-724}
}
Studies were conducted to assess the efficacy and safety of a synthetic peptide-containing surfactant in the treatment of respiratory distress syndrome (RDS) in preterm (approximately 80% of normal gestation) infant rhesus monkeys. Surfactant was prepared consisting of the phospholipids dipalmitoylphosphatidyl choline and palmitoyl-oleoyl phosphatidyl glycerol and a synthetic peptide modeled after surfactant protein B (SP-B),“KL4-Surfactant” contained a peptide having the sequence… CONTINUE READING
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