Efficacy of Rebamipide as Adjunctive Therapy in the Treatment of Recurrent Oral Aphthous Ulcers in Patients with Behçet’s Disease
@article{Matsuda2003EfficacyOR, title={Efficacy of Rebamipide as Adjunctive Therapy in the Treatment of Recurrent Oral Aphthous Ulcers in Patients with Behçet’s Disease}, author={T. Matsuda and S. Ohno and S. Hirohata and Y. Miyanaga and H. Ujihara and G. Inaba and S. Nakamura and S. Tanaka and M. Kogure and Y. Mizushima}, journal={Drugs in R & D}, year={2003}, volume={4}, pages={19-28} }
AbstractBackground: Behçet’s disease (BD) is a recurrent inflammatory disease involving chronic recurrent oral aphthous ulcers (aphthae), uveitis, skin lesions and genital ulcers. We prospectively investigated the efficacy of rebamipide, a gastroprotective drug, against oral aphthous ulcers in BD patients.
Methods: In a multicentre, double-blind, placebo-controlled study, 35 patients with BD, having as the main symptom oral aphthosis, were randomised to receive rebamipide 300 mg/day or placebo… CONTINUE READING
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