Efficacy of Rebamipide as Adjunctive Therapy in the Treatment of Recurrent Oral Aphthous Ulcers in Patients with Behçet’s Disease

@article{Matsuda2003EfficacyOR,
  title={Efficacy of Rebamipide as Adjunctive Therapy in the Treatment of Recurrent Oral Aphthous Ulcers in Patients with Behçet’s Disease},
  author={T. Matsuda and S. Ohno and S. Hirohata and Y. Miyanaga and H. Ujihara and G. Inaba and S. Nakamura and S. Tanaka and M. Kogure and Y. Mizushima},
  journal={Drugs in R & D},
  year={2003},
  volume={4},
  pages={19-28}
}
  • T. Matsuda, S. Ohno, +7 authors Y. Mizushima
  • Published 2003
  • Medicine
  • Drugs in R & D
  • AbstractBackground: Behçet’s disease (BD) is a recurrent inflammatory disease involving chronic recurrent oral aphthous ulcers (aphthae), uveitis, skin lesions and genital ulcers. We prospectively investigated the efficacy of rebamipide, a gastroprotective drug, against oral aphthous ulcers in BD patients. Methods: In a multicentre, double-blind, placebo-controlled study, 35 patients with BD, having as the main symptom oral aphthosis, were randomised to receive rebamipide 300 mg/day or placebo… CONTINUE READING
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