Efficacy of Rapamycin in Tuberous Sclerosis-Associated Hypopigmented Macules: Back to the Future.


The study byWataya-Kaneda et al1 in this issue of JAMADermatology examines the response of hypopigmented macules in tuberous sclerosis (TS) to topical rapamycin. The authors found that topical rapamycin, 0.2%, gel led to substantial improvementofhypopigmented macules without systemic absorption and that the improvementwasmoremarked in sun-exposed skin. This… (More)
DOI: 10.1001/jamadermatol.2014.4299


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