Efficacy of Quetiapine Monotherapy in Posttraumatic Stress Disorder: A Randomized, Placebo-Controlled Trial.

@article{Villarreal2016EfficacyOQ,
  title={Efficacy of Quetiapine Monotherapy in Posttraumatic Stress Disorder: A Randomized, Placebo-Controlled Trial.},
  author={Gerardo Villarreal and Mark B Hamner and Jos{\'e} M. Ca{\~n}ive and Sophie Robert and Lawrence A Calais and Valerie Durklaski and Yusheng Zhai and Clifford Qualls},
  journal={The American journal of psychiatry},
  year={2016},
  volume={173 12},
  pages={1205-1212}
}
OBJECTIVE This was a 12-week randomized, placebo-controlled trial to assess the efficacy of quetiapine monotherapy in the treatment of posttraumatic stress disorder (PTSD). METHOD Eighty patients were randomly assigned to treatment with either quetiapine or placebo. The primary outcome measure was the Clinician-Administered PTSD Scale (CAPS). Secondary efficacy measures included the CAPS subscales, the Davidson Trauma Scale, the Positive and Negative Syndrome Scale (PANSS), the Clinical… CONTINUE READING
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