Efficacy of Prebiotics, Probiotics, and Synbiotics in Irritable Bowel Syndrome and Chronic Idiopathic Constipation: Systematic Review and Meta-analysis

@article{Ford2014EfficacyOP,
  title={Efficacy of Prebiotics, Probiotics, and Synbiotics in Irritable Bowel Syndrome and Chronic Idiopathic Constipation: Systematic Review and Meta-analysis},
  author={A. Ford and E. Quigley and B. Lacy and A. Lembo and Y. Saito and L. Schiller and E. Soffer and B. Spiegel and P. Moayyedi},
  journal={The American Journal of Gastroenterology},
  year={2014},
  volume={109},
  pages={1547-1561}
}
  • A. Ford, E. Quigley, +6 authors P. Moayyedi
  • Published 2014
  • Medicine
  • The American Journal of Gastroenterology
  • OBJECTIVES:Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC) are functional bowel disorders. Evidence suggests that disturbance in the gastrointestinal microbiota may be implicated in both conditions. We performed a systematic review and meta-analysis to examine the efficacy of prebiotics, probiotics, and synbiotics in IBS and CIC.METHODS:MEDLINE, EMBASE, and the Cochrane Controlled Trials Register were searched (up to December 2013). Randomized controlled trials (RCTs… CONTINUE READING

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