Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma

  title={Efficacy of Peptide Receptor Radionuclide Therapy for Functional Metastatic Paraganglioma and Pheochromocytoma},
  author={G. Kong and S. Grozinsky-Glasberg and M. Hofman and J. Callahan and A. Meirovitz and Ofra Maimon and D. Pattison and D. Gross and R. Hicks},
  journal={The Journal of Clinical Endocrinology & Metabolism},
  • G. Kong, S. Grozinsky-Glasberg, +6 authors R. Hicks
  • Published 2017
  • Medicine
  • The Journal of Clinical Endocrinology & Metabolism
  • Purpose: Treatment options for unresectable paraganglioma (PGL)/pheochromocytoma (PCC), especially with uncontrolled secondary hypertension (HTN), are limited. Preliminary studies with peptide receptor radionuclide therapy (PRRT) suggest efficacy, but data on HTN control and survival are lacking. We assessed PRRT outcomes in such patients from two referral centers. Methods: Twenty consecutive patients (13 men; age range, 21 to 77 years) with high somatostatin receptor (SSTR) expression treated… CONTINUE READING
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