Efficacy of Low Dose Clofarabine in Refractory Precursor T- Acute Lymphoblastic Leukemia

Abstract

Refractory T-lymphoblastic leukemia in adults has a poor prognosis in patients who relapse after allogeneic stem cell transplantation, and relatively few new agents have demonstrated activity. Clofarabine is a novel nucleoside analog that has been associated with significant clinical activity in relapsed pediatric B-ALL. We used low dose clofarabine and… (More)

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