Efficacy of Lamivudine or Entecavir on Acute Exacerbation of Chronic Hepatitis B

@inproceedings{Kanda2012EfficacyOL,
  title={Efficacy of Lamivudine or Entecavir on Acute Exacerbation of Chronic Hepatitis B},
  author={Tatsuo Kanda and Masami Shinozaki and Hidehiro Kamezaki and Shuang Wu and Shingo Nakamoto and Makoto Arai and Keiichi Fujiwara and Nobuaki Goto and Fumio Imazeki and Osamu Yokosuka},
  booktitle={International journal of medical sciences},
  year={2012}
}
BACKGROUND/AIMS Spontaneous acute exacerbation of chronic hepatitis B virus (HBV) infection occasionally occurs in its natural history, sometimes leading rapidly to fatal hepatic failure. We compared the effects of lamivudine (LAM) with those of entecavir (ETV) treatments in acute exacerbation of chronic hepatitis B with 500 IU/L or higher alanine aminotransferase (ALT) levels. METHODS Thirty-four patients with acute exacerbation were consecutively treated with LAM /ETV. Their clinical… CONTINUE READING

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