Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review.

@article{Pavenski2013EfficacyOH,
  title={Efficacy of HLA-matched platelet transfusions for patients with hypoproliferative thrombocytopenia: a systematic review.},
  author={Katerina Pavenski and Paolo Rebulla and Ren{\'e} J. Duquesnoy and Chee Loong Saw and Sherrill J. Slichter and Susano Tanael and Nadine Shehata},
  journal={Transfusion},
  year={2013},
  volume={53 10},
  pages={2230-42}
}
BACKGROUND HLA-matched platelets (PLTs) are widely used to transfuse patients but the effectiveness of HLA matching has not been well defined and the cost is approximately five times the cost of preparing the random-donor PLTs. The objective of this systematic review was to determine whether HLA-matched PLTs lead to a reduction in mortality; reduction in frequency or severity of hemorrhage; reduction in HLA alloimmunization, refractoriness, or PLT utilization; or improvement in PLT count… CONTINUE READING

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