Efficacy of Electronic Cigarettes for Smoking Cessation

@article{Orr2014EfficacyOE,
  title={Efficacy of Electronic Cigarettes for Smoking Cessation},
  author={Katherine Kelly Orr and Nicole J Asal},
  journal={Annals of Pharmacotherapy},
  year={2014},
  volume={48},
  pages={1502 - 1506}
}
Objective: To review data demonstrating effective smoking cessation with electronic cigarettes (e-cigarettes). Data Sources: A literature search of MEDLINE/PubMed (1946-March 2014) was performed using the search terms e-cigarettes, electronic cigarettes, and smoking cessation. Additional references were identified from a review of literature citations. Study Selection and Data Extraction: All English-language clinical studies assessing efficacy of e-cigarettes compared with baseline, placebo… 
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TLDR
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How do we determine the impact of e‐cigarettes on cigarette smoking cessation or reduction? Review and recommendations for answering the research question with scientific rigor
AIMS To propose a hierarchy of methodological criteria to consider when determining whether a study provides sufficient information to answer the question of whether e-cigarettes can facilitate
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  • 2014
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Electronic cigarettes for smoking cessation.
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The safety and effect of using ECs to help people who smoke achieve long-term smoking abstinence and the main outcome measure was abstinence from smoking after at least six months follow-up is evaluated.
Successful Nicotine Intake in Medical Assisted Use of E-Cigarettes: A Pilot Study
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The proposed medically assisted training program of e-cig use led to a successful nicotine intake, lack of typical cigarette craving and overdosage symptoms and a significant decrease in the biomarker of cigarette combustion products.
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Cell culture and experimental animal data indicate that e-cigs have the potential for inducing inflammation, albeit much less than smoking, and a focus on human lung biomarkers is focused on.
Electronic nicotine delivery devices, and their impact on health and patterns of tobacco use: a systematic review protocol
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A protocol for an ongoing comprehensive review of the published scientific literature on ENDS is described, using the National Library of Medicine's PubMed electronic database to search for relevant articles.
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References

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Effect of an electronic nicotine delivery device (e-Cigarette) on smoking reduction and cessation: a prospective 6-month pilot study
TLDR
The use of e-Cigarette substantially decreased cigarette consumption without causing significant side effects in smokers not intending to quit, and perception and acceptance of the product was good.
Electronic cigarettes for smoking cessation: a randomised controlled trial
The emerging phenomenon of electronic cigarettes
TLDR
The health effects of using electronic cigarettes are examined, with consideration given to the acceptability, safety and effectiveness of this product to serve as a long-term substitute for smoking or as a tool for smoking cessation.
Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial
TLDR
The 16 mg Ruyan V8 ENDD alleviated desire to smoke after overnight abstinence, was well tolerated and had a pharmacokinetic profile more like the Nicorette inhalator than a tobacco cigarette.
Impact of an Electronic Cigarette on Smoking Reduction and Cessation in Schizophrenic Smokers: A Prospective 12-Month Pilot Study
TLDR
It is shown for the first time that the use of e-cigarette substantially decreased cigarette consumption without causing significant side effects in chronic schizophrenic patients who smoke not intending to quit.
Calls to Poison Centers for Exposures to Electronic Cigarettes — United States, September 2010–February 2014
TLDR
Although e-cigarette use is increasing among U.S. adolescents and adults, its overall impact on public health remains unclear and one area of concern is the potential of e-cigarettes to cause acute nicotine toxicity.
OF HEALTH AND HUMAN SERVICES Food and Drug Administration
TLDR
Evaluated results and behaviors and sexual activities will be used to examine experiences of participants in the RCT.
E-cigarettes a Scientific Review Contemporary Reviews in Cardiovascular Medicine Grana Et Al E-cigarettes: a Scientific Review 1973 Marketing and Media Research as with Adult Population-based Studies, Data Figure 2. Studies Screened and Selected for Inclusion. Prisma Indicates Preferred Reporting It
TLDR
To minimize the potential negative impacts on prevention and cessation and the undermining of existing tobacco control measures, e-cigarette use should be prohibited where tobacco cigarette use is prohibited, and the products should be subject to the same marketing restrictions as tobacco cigarettes.
EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as Tobacco Cigarettes Substitute: A Prospective 12-Month Randomized Control Design Study
TLDR
In smokers not intending to quit, the use of e-cigarettes, with or without nicotine, decreased cigarette consumption and elicited enduring tobacco abstinence without causing significant side effects.
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