Efficacy of 5% Minoxidil versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss

  title={Efficacy of 5\% Minoxidil versus Combined 5\% Minoxidil and 0.01\% Tretinoin for Male Pattern Hair Loss},
  author={Hyoseung Shin and Chong Hyun Won and Seung Ho Lee and Oh Sang Kwon and Kyu Han Kim and Hee Chul Eun},
  journal={American Journal of Clinical Dermatology},
AbstractBackground: 5% topical minoxidil solution has been widely used to stimulate new hair growth and help stop hair loss in men with androgenetic alopecia (AGA). However, it is not convenient for patients to continue applying the solution twice daily on a regular basis. Tretinoin is known to increase the percutaneous absorption of minoxidil and, therefore, to enhance the response of AGA to minoxidil. For this reason, it was assumed that tretinoin would be helpful in alleviating the… 

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Application of minoxidil 5% + chamomile 7% topical solution on human volunteers has not shown any adverse effects and these formulations could be recommended to use.

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Topical Minoxidil 5% is equally effective to combination of topical MinoxIDil 5%, azelaic acid 1.5% and tretinoin 0.01% in treatment of androgenetic alopecia.

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Both spironolactone as a 5% topical solution and minoxidil as a5% topical solutions might be used safely in a twice-daily dosage to treat AGA in both genders, combining them in a single topical dose form can boost efficacy and yield greater advantages.

Use of adapalene in alopecia areata: Efficacy and safety of mometasone furoate 0.1% cream versus combination of mometasone furoate 0.1% cream and adapalene 0.1% gel in alopecia areata

  • M. Unal
  • Medicine
    Dermatologic therapy
  • 2018
Adapalene can be used as a new therapeutic modality in AA and is revealed the efficacy and safety of adapalenes and mometasone furoate combination in AA.

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Mesotherapy, containing nutritional supplements only, is an effective, more acceptable to patients, and more tolerable modality compared with topical minoxidil in the treatment of FPHL.

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