Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis
@article{Kotecha2015EfficacyO, title={Efficacy of β blockers in patients with heart failure plus atrial fibrillation: an individual-patient data meta-analysis}, author={D. Kotecha and J. Holmes and H. Krum and D. Altman and on behalf of the Beta-Blockers in Heart Failure Colla Group}, journal={The Lancet}, year={2015}, volume={384}, pages={2235-2243} }
BACKGROUND
Atrial fibrillation and heart failure often coexist, causing substantial cardiovascular morbidity and mortality. β blockers are indicated in patients with symptomatic heart failure with reduced ejection fraction; however, the efficacy of these drugs in patients with concomitant atrial fibrillation is uncertain. We therefore meta-analysed individual-patient data to assess the efficacy of β blockers in patients with heart failure and sinus rhythm compared with atrial fibrillation… CONTINUE READING
Supplemental Clinical Trials
Observational Clinical Trial
Several large trials have shown that beta-blocker treatment reduces the risk of death and
hospital admission in patients with symptomatic heart failure. Unfortunately, survey data… Expand
Conditions | Heart Failure |
---|---|
Intervention | Drug, Other |
Figures, Tables, and Topics from this paper
Paper Mentions
Interventional Clinical Trial
Atrial fibrillation is a common heart rhythm disturbance, causing important discomfort for
patients, a high risk of stroke, frequent hospital admissions and a two-fold increase in… Expand
Conditions | Permanent Atrial Fibrillation |
---|---|
Intervention | Drug |
299 Citations
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