Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging

Abstract

We evaluated the pre-clinical efficacy of a novel intraperitoneal (i.p.) sustained-release paclitaxel formulation (PTXePC) using bioluminescent imaging (BLI) in the treatment of ovarian cancer. Human ovarian carcinoma cells stably expressing the firefly luciferase gene (SKOV3Luc) were injected i.p. into SCID mice. Tumour growth was evaluated during… (More)
DOI: 10.1038/sj.bjc.6604803

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@article{Vassileva2008EfficacyAO, title={Efficacy assessment of sustained intraperitoneal paclitaxel therapy in a murine model of ovarian cancer using bioluminescent imaging}, author={Vessela Vassileva and Eduardo H. Moriyama and Rocheli de Souza and Jonathan W Grant and Christine Allen and Brian C. Wilson and Micheline Piquette-Miller}, journal={British Journal of Cancer}, year={2008}, volume={99}, pages={2037 - 2043} }