Efficacy and treatment satisfaction of once-daily insulin glargine plus one or two oral antidiabetic agents versus continuing premixed human insulin in patients with Type 2 diabetes previously on long-term conventional insulin therapy: the SWITCH Pilot Study.

@article{Schiel2008EfficacyAT,
  title={Efficacy and treatment satisfaction of once-daily insulin glargine plus one or two oral antidiabetic agents versus continuing premixed human insulin in patients with Type 2 diabetes previously on long-term conventional insulin therapy: the SWITCH Pilot Study.},
  author={R. O. Schiel and Ulrich Alfons M{\"u}ller},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  year={2008},
  volume={116 1},
  pages={58-64}
}
BACKGROUND Addition of the long-acting basal human insulin analogue insulin glargine (LANTUS) to the treatment regimen of patients with inadequate glycaemic control on oral antidiabetic drugs (OADs) alone has previously been evaluated as effective, safe and convenient. This pilot study aimed to establish whether insulin glargine plus OADs is effective in Type 2 diabetes patients previously poorly controlled on premixed insulin therapy. METHODS In an open, controlled, randomized, parallel… CONTINUE READING

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